A Clinician’s Handbook for Childhood & Adult Immunizations in Georgia

RSV – mRESVIA

Pathophysiology

Similarly to some other respiratory infections, a cough or sneeze easily spreads RSV.

Typically, contagious for 3-8 days – people with weakened immune systems can be contagious as long as 4 weeks after symptoms gone

Vaccine Description

MRESVIATM is a vaccine indicated for active immunization for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV) in individuals 60 years of age and older

Administration Schedule/Dose

Storage & Handling

  • Must be stored frozen (between -40⁰C and -15⁰C)
  • Must be stored refrigerated (between 2⁰C and 8⁰C)
  • During storage, minimize exposure to room light, and avoid exposure to direct sunlight and ultraviolet light

 

 Storage after Thawing

  • Pre-filled plastic syringes may be stored refrigerated between 2°C to 8°C (36°F to 46°F) for up to 30 days prior to use. Storage at 8°C to 25°C (46°F to 77°F):
  • Pre-filled plastic syringes may be stored between 8°C to 25°C (46°F to 77°F) for a total of 24 hours after removal from refrigerated conditions. Discard the pre-filled syringe if not used within this time. Syringes should not be returned to the refrigerator after being thawed at room temperature.
  • Total storage at 8°C to 25°C (46°F to 77°F) must not exceed 24 hours.
  • Do not refreeze once thawed. Do not shake.

Contraindications

Do not administer MRESVIA to individuals with a history of a severe allergic reaction (e.g., anaphylaxis) to any component of MRESVIA.

Special Instructions

  • People with minor illnesses, such as a cold, may be vaccinated. People who are moderately or severely ill should usually wait until they recover before getting RSV vaccine

*See information for AREXVY and ABRYSVO